Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2521742 | 0.91 | FAAH (0.38) | FAAHMGAMGAASIMGAM2 | |
| Butane SCHEMBL23607922 | 0.86 | FAAH (0.54) | FAAHNAAADGKAPAMRAD52 | |
| Butane SCHEMBL6079989 | 0.85 | FAAH (0.57) | FAAHNAAADGKAPAMRAD52 | |
| Butane SCHEMBL10792124 | 0.85 | FAAH (0.57) | FAAHNAAADGKAPAMRAD52 | |
| Butane SCHEMBL452621 | 0.85 | GAA (0.44) | FAAHMGAMGAASIMGAM2 | |
| SCHEMBL240283 | 0.82 | GAA (0.46) | FAAHMGAMGAASIMGAM2 | |
| Butane SCHEMBL455717 | 0.81 | ALDH1A1 (0.52) | FAAHALDH1A1NAAADGKAPAM | |
| SCHEMBL3193354 | 0.80 | GAA (0.44) | FAAHMGAMGAASIMGAM2 | |
| SCHEMBL3190803 | 0.80 | GAA (0.44) | FAAHMGAMGAASIMGAM2 | |
| Hydrochloric Acid SCHEMBL10891744 | 0.80 | GAA (0.44) | FAAHMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |
| US-5463111-A | Process for preparing dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |