Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23607924 | 0.86 | TDP1 (0.38) | ALDH1A1TRPA1TDP1MEN1KMT2A | |
| SCHEMBL10792129 | 0.85 | FAAH (0.38) | ALDH1A1TRPA1TDP1MEN1KMT2A | |
| SCHEMBL6079996 | 0.85 | FAAH (0.38) | ALDH1A1TRPA1TDP1MEN1KMT2A | |
| SCHEMBL230068 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TRPA1TDP1MEN1KMT2A | |
| SCHEMBL452623 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL27522636 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TRPA1TDP1MEN1KMT2A | |
| SCHEMBL26658212 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TRPA1TDP1MEN1KMT2A | |
| SCHEMBL28077349 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TRPA1TDP1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27830684 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TRPA1TDP1MEN1KMT2A | |
| SCHEMBL28054134 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TRPA1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |
| US-5463111-A | Process for preparing dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |