Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 6/20 | 0.49 |
| ▸ | F3 | P13726 | 6/20 | 0.49 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | PPARD | Q03181 | 5/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065856 | 1.00 | TBXAS1 (0.56) | TBXAS1LTB4RLTB4R2F7F3 | |
| SCHEMBL1006879 | 0.98 | TBXAS1 (0.55) | TBXAS1LTB4RLTB4R2F7F3 | |
| SCHEMBL1006878 | 0.98 | TBXAS1 (0.55) | TBXAS1LTB4RLTB4R2F7F3 | |
| SCHEMBL10988834 | 0.90 | TBXAS1 (0.47) | TBXAS1LTB4RLTB4R2F7F3 | |
| SCHEMBL10988837 | 0.90 | TBXAS1 (0.47) | TBXAS1LTB4RLTB4R2F7F3 | |
| SCHEMBL10988831 | 0.90 | TBXAS1 (0.47) | TBXAS1LTB4RLTB4R2F7F3 | |
| SCHEMBL9421120 | 0.89 | FASN (0.49) | TBXAS1LTB4RLTB4R2F7F3 | |
| SCHEMBL727447 | 0.88 | HSD11B1 (0.50) | TBXAS1PPARGFFAR1PTGS1ALDH1A1 | |
| SCHEMBL2043779 | 0.88 | HSD11B1 (0.50) | TBXAS1PPARGFFAR1PTGS1ALDH1A1 | |
| SCHEMBL727448 | 0.88 | HSD11B1 (0.50) | TBXAS1PPARGFFAR1PTGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537954-B1 | Process of preparing diphenylmethane derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-07-24 | — | — | EP | disclosed |
| US-5235091-A | Reacting a phenol compound with a stilbene compound in presence of methanesulfonic acid | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0537954-A1 | Process of preparing diphenylmethane derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |