SCHEMBL9065916

SCHEMBL9065916

CC(C)c1ccccc1C1=C([Zr]C2=C(c3ccccc3C(C)C)C=CC2)CC=C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
FAAH O00519 2/20 0.32
MGLL Q99685 1/20 0.32
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7566172 0.98 CA1 (0.34) CA1CA2CA12CA9GABRA1
SCHEMBL9066417 0.79 NPC1 (0.33) TSHR
Hydrochloric Acid SCHEMBL7566926 0.77 NPC1 (0.32) TSHR
Hydrochloric Acid SCHEMBL27515129 0.76 CA1 (0.35) CA1CA2CA12CA9GABRA1
Hydrochloric Acid SCHEMBL27515128 0.76 CA1 (0.35) CA1CA2CA12CA9GABRA1
SCHEMBL9066114 0.75 CYP2D6 (0.36) GABRA1GABRB2MGLLLMNATSHR
Hydrochloric Acid SCHEMBL7566166 0.75 CA1 (0.37) CA1CA2CA12CA9GABRA1
SCHEMBL7740532 0.74 ALDH1A1 (0.33)
Hydrochloric Acid SCHEMBL7567523 0.73 CYP2D6 (0.35) MGLLLMNATRPA1
SCHEMBL29002030 0.72 CA12 (0.33) CA1CA2CA12CA9GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540108-B1 Catalyst composition SHELL INT RESEARCH (NL) 1996-01-03 EP claimed