Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 7/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | HSD17B7 | P56937 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065981 | 1.00 | SHBG (0.51) | SHBGARKMT2ASRD5A1SRD5A2 | |
| SCHEMBL9066087 | 0.85 | AR (0.49) | SHBGARKMT2ASRD5A1SRD5A2 | |
| SCHEMBL9066083 | 0.85 | AR (0.49) | SHBGARKMT2ASRD5A1SRD5A2 | |
| SCHEMBL9066033 | 0.83 | AR (0.47) | SHBGARKMT2ASRD5A1SRD5A2 | |
| SCHEMBL9066031 | 0.76 | AR (0.46) | SHBGARKMT2ASRD5A1SRD5A2 | |
| SCHEMBL13656758 | 0.76 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL4265528 | 0.76 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL4265525 | 0.76 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL7751282 | 0.76 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL8528297 | 0.75 | HSD17B7 (0.42) | SHBGSRD5A1SRD5A2HSD17B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494914-A | USEFUL FOR TREATMENT OF DISEASES WHOSE PROGRESS IS AIDED BY ACTIVATION OF ANDROGEN RECEPTORS | ENDORECHERCHE (CA) | 1996-02-27 | — | — | US | claimed |