Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256069 | 0.82 | NQO1 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 | |
| SCHEMBL10795812 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 | |
| SCHEMBL16974437 | 0.81 | ADRA2A (0.61) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 | |
| SCHEMBL2524557 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 | |
| SCHEMBL31127390 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 | |
| SCHEMBL3255966 | 0.80 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 | |
| SCHEMBL10416031 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 | |
| SCHEMBL264358 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 | |
| SCHEMBL5609867 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 | |
| SCHEMBL20957507 | 0.78 | ALDH1A1 (0.61) | ALDH1A1CYP1A2CYP2C9CYP2C19AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524686-B1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | POLA CHEM IND INC (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-9066914-B2 | Prophylactic or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-06-30 | — | — | US | disclosed |
| EP-2524686-A1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | Pola Chemical Industries Inc. (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-11-08 | — | — | US | disclosed |
| CN-1142932-C | N,N-dimethyl-1-t-butoxycarbonyl-4-phenylpiperidine-4-carboxamide | ������������ʽ���� | 2004-03-24 | — | — | CN | disclosed |
| EP-0441383-B1 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5183870-A | A curable polybutylene glycol di(meth)acrylate, a urethane or epoxy (meth)acrylate and a (meth)acrylate; heat and water resistance; impact strength; dyeability; workability | MITSUBISHI RAYON CO., LTD (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0441383-A2 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, NQO1 | ALDH1A1 136/4885CYP1A2 1165/4885CYP2C9 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.