Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 11/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3446776 | 0.94 | CA2 (0.65) | CA2MAPK1FOLH1SLC1A2SLC1A1 | |
| SCHEMBL27656177 | 0.92 | CA2 (0.63) | CA2MAPK1FOLH1SLC1A2SLC1A1 | |
| Ethylene Glycol SCHEMBL10337849 | 0.89 | FFAR4 (0.58) | CA2MAPK1FOLH1TDP1AKR1B1 | |
| SCHEMBL27995377 | 0.89 | FOLH1 (0.65) | CA2MAPK1FOLH1SLC1A2SLC1A1 | |
| SCHEMBL8653950 | 0.88 | FOLH1 (0.66) | CA2MAPK1FOLH1SLC1A2SLC1A1 | |
| Ethylene Glycol SCHEMBL27551639 | 0.87 | FFAR4 (0.56) | CA2MAPK1FOLH1TDP1AKR1B1 | |
| SCHEMBL337293 | 0.86 | FOLH1 (0.67) | FOLH1TDP1GRIK1GRIK2 | |
| SCHEMBL1506904 | 0.86 | FOLH1 (0.67) | FOLH1TDP1GRIK1GRIK2 | |
| SCHEMBL1506839 | 0.86 | FOLH1 (0.67) | FOLH1TDP1GRIK1GRIK2 | |
| SCHEMBL1134819 | 0.86 | FOLH1 (0.67) | FOLH1TDP1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521273-A | POLYUREAURETHANE COPOLYMER | TH. GOLDSCHMIDT AG (DE) | 1996-05-28 | — | — | US | disclosed |
| US-5461122-A | Consists of four soft segments: polyethylene glycol, polytetramethylene, polycaprolactone-polydimethylsiloxane-polycaprolactone, soft segments are linked with diisocyanate and chain extended with a diamine | TH. GOLDSCHMIDT AG (DE) | 1995-10-24 | — | — | US | disclosed |
| US-5389430-A | A breathable adhesive comprising a polyurethane/-ether/-ester/ urea segmented block polymer and a breathable polyurethaneurea top coat; medical clothing; heat, oxidation and UV resistance; nonhydrolyzing | TH. GOLDSCHMIDT AG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0609730-A1 | Waterproof, moisture vapor permeable polymers, films and coated textiles and other materials | Th. Goldschmidt AG (DE) | 1994-08-10 | — | — | EP | disclosed |