Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 3/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634780 | 0.95 | EPHX2 (0.54) | EPHX2TSHRNAAADGKAMAPT | |
| SCHEMBL634781 | 0.87 | EPHX2 (0.43) | EPHX2TSHR | |
| SCHEMBL8084596 | 0.84 | TSHR (0.57) | EPHX2TSHRNAAANPSR1 | |
| SCHEMBL5709873 | 0.81 | TSHR (0.47) | EPHX2TSHRNAAAMAPTMAPK1 | |
| SCHEMBL30304082 | 0.81 | NAAA (0.46) | TSHRNAAAMAPTMAPK1NPSR1 | |
| SCHEMBL15287645 | 0.81 | NAAA (0.46) | TSHRNAAAMAPTMAPK1NPSR1 | |
| SCHEMBL30304015 | 0.81 | NAAA (0.46) | TSHRNAAAMAPTMAPK1NPSR1 | |
| SCHEMBL28825960 | 0.81 | TSHR (0.52) | TSHRNAAANPSR1L3MBTL1 | |
| SCHEMBL11576818 | 0.79 | NAAA (0.52) | EPHX2TSHRNAAADGKAMAPT | |
| SCHEMBL9847336 | 0.79 | TSHR (0.45) | EPHX2TSHRNAAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432124-B1 | Plasticizer composition, plasticized polyvinyl butyral and interlayer thereof | MONSANTO CO (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5013780-A | Plasticized polyvinyl butyral and interlayer thereof | MONSANTO COMPANY (US) | 1991-05-07 | — | — | US | disclosed |
| US-5013779-A | Cyclohexyl adipate plasticizer, radiation resistance | MONSANTO COMPANY (US) | 1991-05-07 | — | — | US | disclosed |