Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL2506708 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetone SCHEMBL2568997 | 0.97 | ALDH1A1 (0.40) | ALDH1A1TSHRLMNATDP1THPO | |
| Butanone SCHEMBL28162644 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetic Acid SCHEMBL10486550 | 0.90 | FFAR3 (0.47) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetone SCHEMBL4800994 | 0.88 | ALDH1A1 (0.33) | ALDH1A1TSHRLMNATDP1THPO | |
| Butanone SCHEMBL28158094 | 0.87 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNATDP1THPO | |
| Butanol SCHEMBL21407620 | 0.87 | TSHR (0.62) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetone SCHEMBL27823580 | 0.86 | ALDH1A1 (0.32) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetone SCHEMBL19056239 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNATDP1TP53 | |
| Acetone SCHEMBL153745 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10312001-B2 | Patterned overcoated nanowire transparent conducting coatings | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-06-04 | — | — | US | disclosed |
| US-20170278594-A1 | PATTERNED OVERCOATED NANOWIRE TRANSPARENT CONDUCTING COATINGS | 3M INNOVATIVE PROPERTIES CO (US) | 2017-09-28 | — | — | US | disclosed |
| US-9711263-B2 | Corona patterning of overcoated nanowire transparent conducting coatings | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-9603242-B2 | Laser patterning of silver nanowire-based transparent electrically conducting coatings | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150076106-A1 | CORONA PATTERNING OF OVERCOATED NANOWIRE TRANSPARENT CONDUCTING COATINGS | 3M INNOVATIVE PROPERTIES COMPANY | 2015-03-19 | — | — | US | disclosed |
| US-20140332254-A1 | LASER PATTERNING OF SILVER NANOWIRE - BASED TRANSPARENT ELECTRICALLY CONDUCTING COATINGS | 3M INNOVATIVE PROPERTIES COMPANY | 2014-11-13 | — | — | US | disclosed |
| WO-2013173070-A1 | CORONA PATTERNING OF OVERCOATED NANOWIRE TRANSPARENT CONDUCTING COATINGS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-11-21 | — | — | WO | disclosed |
| WO-2013095971-A1 | LASER PATTERNING OF SILVER NANOWIRE - BASED TRANSPARENT ELECTRICALLY CONDUCTING COATINGS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-06-27 | — | — | WO | disclosed |
| EP-0381349-B1 | Pressure-sensitive film composite having improved adhesion to plasticized vinyl substrates | MINNESOTA MINING & MFG (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0381349-A2 | Pressure-sensitive film composite having improved adhesion to plasticized vinyl substrates | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-08-08 | — | — | EP | disclosed |