Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL9066475 | 0.97 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetone SCHEMBL2506708 | 0.97 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetone SCHEMBL4800994 | 0.91 | ALDH1A1 (0.33) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetone SCHEMBL27823580 | 0.89 | ALDH1A1 (0.32) | ALDH1A1TSHRLMNATDP1THPO | |
| Butanone SCHEMBL28162644 | 0.88 | ALDH1A1 (0.59) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetic Acid SCHEMBL10486550 | 0.87 | FFAR3 (0.47) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetone SCHEMBL970686 | 0.86 | LMNA (0.55) | ALDH1A1TSHRLMNATDP1THPO | |
| Acetone SCHEMBL3956179 | 0.86 | — | — | |
| Isopropyl Alcohol SCHEMBL17180 | 0.86 | — | — | |
| Acetone SCHEMBL10426278 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TSHRLMNATDP1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108315375-B | Production method of oxidized nicotinamide adenine dinucleotide phosphate | 山东睿智医药科技有限公司 | 2021-10-12 | — | — | CN | claimed |
| CN-108315375-A | A kind of production method of oxidized nicotinamide adenine dinucleotide phosphate | 菏泽睿智科技开发有限公司 | 2018-07-24 | — | — | CN | claimed |
| CN-114113372-A | Method for detecting residual solvent of natural edible pigment | 拱北海关技术中心 | 2022-03-01 | — | — | CN | disclosed |
| CN-108315375-B | Production method of oxidized nicotinamide adenine dinucleotide phosphate | 山东睿智医药科技有限公司 | 2021-10-12 | — | — | CN | disclosed |
| EP-3417027-A1 | METHOD FOR PRODUCING AN ADHESIVE TAPE BY MEANS OF PLASMA LAMINATION | tesa SE (DE) | 2018-12-26 | — | — | EP | disclosed |
| EP-3417026-A1 | MAKING ADHESIVE SILICONE SUBSTANCES ADHERE TO FLUOROPOLYMER FILMS USING A CORONA TREATMENT | tesa SE (DE) | 2018-12-26 | — | — | EP | disclosed |
| CN-108315375-A | A kind of production method of oxidized nicotinamide adenine dinucleotide phosphate | 菏泽睿智科技开发有限公司 | 2018-07-24 | — | — | CN | disclosed |
| EP-2382174-A2 | CONVERSION OF CARBON DIOXIDE TO ORGANIC PRODUCTS | The Trustees of the University of Princeton (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010088524-A2 | CONVERSION OF CARBON DIOXIDE TO ORGANIC PRODUCTS | PRINCETON UNIVERSITY (US) | 2010-08-05 | — | — | WO | disclosed |