Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8367714 | 1.00 | — | — | |
| SCHEMBL16039 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL11568933 | 0.84 | — | — | |
| SCHEMBL2998640 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL9066948 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL11809184 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL10509843 | 0.80 | — | — | |
| SCHEMBL2997147 | 0.80 | — | — | |
| SCHEMBL2988878 | 0.80 | — | — | |
| Water SCHEMBL29701019 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927195-B2 | Olefin coordination polymerization catalyst and use thereof | PETROCHINA COMPANY LIMITED (CN) | 2021-02-23 | — | — | US | claimed |
| US-20190248928-A1 | Olefin Coordination Polymerization Catalyst and Use Thereof | PETROCHINA COMPANY LIMITED (CN) | 2019-08-15 | — | — | US | claimed |
| US-10927195-B2 | Olefin coordination polymerization catalyst and use thereof | PETROCHINA COMPANY LIMITED (CN) | 2021-02-23 | — | — | US | disclosed |
| US-20190248928-A1 | Olefin Coordination Polymerization Catalyst and Use Thereof | PETROCHINA COMPANY LIMITED (CN) | 2019-08-15 | — | — | US | disclosed |
| US-20160009830-A1 | SUPPORTED POLYOLEFIN CATALYST AND PREPARATION AND APPLICATION THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2016-01-14 | — | — | US | disclosed |
| EP-0599355-B1 | Catalysts for polymerization of olefins | CHISSO CORP (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0412696-B1 | Method for the preparation of catalyst components for the polymerization of ethylene to produce a polymer with a relatively narrow molecule weight distribution | BOREALIS HOLDING AS (DK) | 1995-12-13 | — | — | EP | disclosed |
| US-5322830-A | Coordination catalyst | NESTE OY (FI) | 1994-06-21 | — | — | US | disclosed |
| EP-0599355-A1 | Catalysts for polymerization of olefins | CHISSO CORPORATION (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5084429-A | Coordination catalysts for olefin polymerization from magnesium, titanium, vanadium and silicon compounds | CHISSO CORPORATION (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0415704-A2 | Catalysts for polymerization of olefins | CHISSO CORPORATION (JP) | 1991-03-06 | — | — | EP | disclosed |
| EP-0412696-A2 | Method for the preparation of catalyst components for the polymerization of ethylene to produce a polymer with a relatively narrow molecule weight distribution | BOREALIS A/S (DK) | 1991-02-13 | — | — | EP | disclosed |