SCHEMBL9066580

SCHEMBL9066580

Sc1ccc2ccccc2c1[Ag]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.50
ALDH1A1 P00352 5/20 0.50
CYP2A6 P11509 5/20 0.50
TSHR P16473 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
HPRT1 P00492 3/20 0.46
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.42
CYP1A2 P05177 5/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTPN22 Q9Y2R2 1/20 0.38
PAX8 Q06710 1/20 0.38
HPGD P15428 2/20 0.37
THRB P10828 1/20 0.37
CYP3A4 P08684 1/20 0.36
KEAP1 Q14145 1/20 0.36
POLB P06746 1/20 0.35
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL561071 0.75 ALDH1A1 (0.55) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL467413 0.75 HSD17B10 (0.55) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL1402459 0.71 CYP2A6 (0.60) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL690649 0.71 HSD17B10 (0.50) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL2773635 0.71 HSD17B10 (0.50) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL31094047 0.71 PTPN22 (0.60) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL1392752 0.71 POLB (0.56) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL94394 0.71 PTPN22 (0.60) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL1393939 0.71 CYP2A6 (0.50) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL1392923 0.71 CYP2A6 (0.60) HSD17B10ALDH1A1CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727427-A1 ANTIBACTERIAL, ANTIFUNGAL AND ANTIVIRAL AGENT MEIJI MILK PRODUCTS COMPANY LIMITED (JP) 1996-08-21 EP disclosed