Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | G6PD | P11413 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655314 | 0.82 | VDR (0.48) | CYP3A4LMNAGABRPGABRDG6PD | |
| SCHEMBL3655313 | 0.82 | VDR (0.48) | CYP3A4LMNAGABRPGABRDG6PD | |
| SCHEMBL3653135 | 0.82 | VDR (0.48) | CYP3A4LMNAGABRPGABRDG6PD | |
| SCHEMBL3653133 | 0.82 | VDR (0.48) | CYP3A4LMNAGABRPGABRDG6PD | |
| SCHEMBL3655510 | 0.82 | LMNA (0.68) | CYP3A4LMNAGABRPGABRDG6PD | |
| SCHEMBL3654366 | 0.82 | LMNA (0.68) | CYP3A4LMNAGABRPGABRDG6PD | |
| SCHEMBL13917761 | 0.82 | LMNA (0.68) | CYP3A4LMNAGABRPGABRDG6PD | |
| SCHEMBL3651742 | 0.82 | LMNA (0.68) | CYP3A4LMNAGABRPGABRDG6PD | |
| SCHEMBL3651739 | 0.82 | LMNA (0.68) | CYP3A4LMNAGABRPGABRDG6PD | |
| SCHEMBL3652170 | 0.82 | LMNA (0.68) | CYP3A4LMNAGABRPGABRDG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494914-A | USEFUL FOR TREATMENT OF DISEASES WHOSE PROGRESS IS AIDED BY ACTIVATION OF ANDROGEN RECEPTORS | ENDORECHERCHE (CA) | 1996-02-27 | — | — | US | disclosed |
| EP-0641211-A1 | INHIBITORS OF TESTOSTERONE 5$g(a)-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993023053-A1 | INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1993-11-25 | — | — | WO | disclosed |