Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668000 | 1.00 | MAPK1 (0.61) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL11111824 | 0.91 | TP53 (0.53) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL11807025 | 0.87 | ALDH1A1 (0.53) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL5175932 | 0.87 | ALDH1A1 (0.53) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL11805233 | 0.87 | ALDH1A1 (0.53) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL11799712 | 0.83 | ALDH1A1 (0.50) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL29634762 | 0.82 | ALDH1A1 (0.53) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL9329189 | 0.82 | ALDH1A1 (0.53) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL123908 | 0.81 | ALDH1A1 (0.91) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL16248483 | 0.80 | HCAR2 (0.55) | MAPK1HIF1AALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612773-B1 | Thermoplastic resin composition and process for preparing modified polyolefin type resin | MITSUBISHI CHEM CORP (JP) | 1996-12-27 | — | — | EP | disclosed |
| US-5424359-A | Aromatic vinyl polymer having alpha, beta-unsaturated carboxylate having a hydroxyl group grafted onto it, and saturated polyester | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0612773-A1 | Thermoplastic resin composition and process for preparing modified polyolefin type resin | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-08-31 | — | — | EP | disclosed |