Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 5/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27732628 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL9066766 | 1.00 | — | — | |
| Phosphoric Acid SCHEMBL27849589 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL10887747 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL28747802 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL9391422 | 0.96 | ALDH1A1 (0.55) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL1686181 | 0.96 | ALDH1A1 (0.55) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL173991 | 0.96 | — | — | |
| Phosphoric Acid SCHEMBL28713229 | 0.96 | ALDH1A1 (0.55) | ALDH1A1TSHRCA2PPARDFDPS | |
| Phosphoric Acid SCHEMBL27521724 | 0.96 | ALDH1A1 (0.55) | ALDH1A1TSHRCA2PPARDFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112121228-B | Bone defect cavity filling implant | 山东第一医科大学附属省立医院(山东省立医院) | 2021-04-09 | — | — | CN | disclosed |
| CN-112121228-A | Bone defect cavity filling implant | 仇申强 | 2020-12-25 | — | — | CN | disclosed |
| CN-101316810-A | Ionic liquids | BIONIQS LTD (GB) | 2008-12-03 | — | — | CN | disclosed |
| EP-0526444-B1 | Herbicidal compositions | MONSANTO CO (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5430005-A | N-phosphonomethyglycine salt, quaternary ammonium compound, polypropylene glycol | MONSANTO COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0526444-A1 | Herbicidal compositions | MONSANTO COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |