Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2533715 | 0.82 | TDP1 (0.45) | LMNAKMT2AALDH1A1 | |
| SCHEMBL1930837 | 0.75 | F2 (0.48) | BCHEAPOBEC3AAPOBEC3GCHRNA7LMNA | |
| SCHEMBL2574686 | 0.74 | CHRNA7 (0.50) | BCHEAPOBEC3AAPOBEC3GCHRNA7LMNA | |
| SCHEMBL1088261 | 0.73 | TDP1 (0.45) | CHRNA7LMNAMEN1KMT2ATSHR | |
| SCHEMBL1087816 | 0.73 | TDP1 (0.45) | CHRNA7LMNAMEN1KMT2ATSHR | |
| SCHEMBL1087819 | 0.73 | TDP1 (0.45) | CHRNA7LMNAMEN1KMT2ATSHR | |
| SCHEMBL10338863 | 0.73 | BCHE (0.53) | BCHEAPOBEC3AAPOBEC3GCHRNA7LMNA | |
| SCHEMBL30669504 | 0.72 | CHRNA7 (0.49) | APOBEC3AAPOBEC3GCHRNA7LMNAF2 | |
| SCHEMBL11632239 | 0.72 | BCHE (0.46) | BCHEAPOBEC3AAPOBEC3GCHRNA7LMNA | |
| SCHEMBL10995636 | 0.72 | BCHE (0.51) | BCHEAPOBEC3AAPOBEC3GCHRNA7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587480-A | TREATING HIV AND HEPATITIS VIRUS INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 1996-12-24 | — | — | US | disclosed |