Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734285 | 0.85 | PTPN11 (0.50) | PTPN11GAAPOLBCASP6TSHR | |
| SCHEMBL28243904 | 0.78 | HTT (0.42) | PTPN11POLBCASP6RARARARB | |
| SCHEMBL11647099 | 0.77 | ALDH1A1 (0.55) | PTPN11POLBCASP6TSHRRARA | |
| SCHEMBL11032964 | 0.76 | TSHR (0.46) | GAATSHRCA12CA1CA2 | |
| SCHEMBL28473308 | 0.76 | POLB (0.38) | PTPN11POLBCASP6TSHRRARA | |
| SCHEMBL8398812 | 0.75 | KDM4E (0.53) | GAAPOLBTSHRCA12CA1 | |
| SCHEMBL25375627 | 0.74 | EP300 (0.45) | PTPN11GAAPOLBCASP6TSHR | |
| SCHEMBL31401228 | 0.74 | TSHR (0.51) | PTPN11POLBCASP6TSHRRARB | |
| SCHEMBL30622549 | 0.73 | TSHR (0.71) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL617974 | 0.73 | TSHR (0.71) | POLBCASP6TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565270-A | SOLVENT-FREE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |