Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1864858 | 0.79 | GRIN2D (0.43) | ADRB2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4720996 | 0.74 | GRIN2D (0.40) | ADRB2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27644891 | 0.74 | GRIN2D (0.42) | ADRB2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3128296 | 0.74 | FLT3 (0.41) | ADRB2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5012502 | 0.72 | PTGS2 (0.38) | ADRB2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5750248 | 0.72 | TP53 (0.38) | AKT1ALDH1A1MAPK1MAPTTP53 | |
| SCHEMBL4196373 | 0.72 | NFE2L2 (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6041126 | 0.72 | SOAT1 (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2841427 | 0.71 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6822813 | 0.71 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441383-B1 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5183870-A | A curable polybutylene glycol di(meth)acrylate, a urethane or epoxy (meth)acrylate and a (meth)acrylate; heat and water resistance; impact strength; dyeability; workability | MITSUBISHI RAYON CO., LTD (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0441383-A2 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |