Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067155 | 1.00 | LMNA (0.42) | LMNAALDH1A1SLC22A6OR51E2THRB | |
| SCHEMBL9067380 | 1.00 | LMNA (0.42) | LMNAALDH1A1SLC22A6OR51E2THRB | |
| SCHEMBL4929693 | 0.85 | GRIK1 (0.52) | LMNAALDH1A1SLC22A6OR51E2GABRR1 | |
| SCHEMBL4926657 | 0.85 | GRIK1 (0.52) | LMNAALDH1A1SLC22A6OR51E2GABRR1 | |
| SCHEMBL4926664 | 0.85 | GRIK1 (0.52) | LMNAALDH1A1SLC22A6OR51E2GABRR1 | |
| SCHEMBL12767798 | 0.78 | OR51E2 (0.43) | LMNAALDH1A1SLC22A6OR51E2THRB | |
| SCHEMBL1901045 | 0.78 | OR51E2 (0.43) | LMNAALDH1A1SLC22A6OR51E2THRB | |
| SCHEMBL15819973 | 0.78 | OR51E2 (0.43) | LMNAALDH1A1SLC22A6OR51E2THRB | |
| SCHEMBL16205190 | 0.77 | FNTA (0.38) | LMNAALDH1A1SLC22A6OR51E2GABRR1 | |
| SCHEMBL415844 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612773-B1 | Thermoplastic resin composition and process for preparing modified polyolefin type resin | MITSUBISHI CHEM CORP (JP) | 1996-12-27 | — | — | EP | disclosed |
| EP-0612773-A1 | Thermoplastic resin composition and process for preparing modified polyolefin type resin | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-08-31 | — | — | EP | disclosed |