Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926664 | 1.00 | GRIK1 (0.52) | GRIK1LMNAALDH1A1SLC22A6OR51E2 | |
| SCHEMBL4926657 | 1.00 | GRIK1 (0.52) | GRIK1LMNAALDH1A1SLC22A6OR51E2 | |
| SCHEMBL9067155 | 0.85 | LMNA (0.42) | GRIK1LMNAALDH1A1SLC22A6OR51E2 | |
| SCHEMBL9067150 | 0.85 | LMNA (0.42) | GRIK1LMNAALDH1A1SLC22A6OR51E2 | |
| SCHEMBL9067380 | 0.85 | LMNA (0.42) | GRIK1LMNAALDH1A1SLC22A6OR51E2 | |
| SCHEMBL9004254 | 0.84 | GRIK1 (0.37) | GRIK1SLC22A6 | |
| SCHEMBL27220816 | 0.76 | GRIK1 (0.56) | GRIK1ALDH1A1SLC22A6GRIA4GRIK3 | |
| Acetic Acid SCHEMBL30309308 | 0.73 | LMNA (0.40) | LMNAALDH1A1SLC22A6OR51E2MAPT | |
| SCHEMBL7164610 | 0.73 | LMNA (0.35) | LMNAALDH1A1SLC22A6OR51E2MAPT | |
| Pyruvate SCHEMBL30531673 | 0.72 | LMNA (0.53) | LMNAALDH1A1SLC22A6OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390825-B1 | Process for the preparation of oxazolidinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-24 | — | — | US | disclosed |
| US-20080146458-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-19 | — | — | US | disclosed |
| US-20070265451-A1 | Process for the preparation of oxazolidinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-11-15 | — | — | US | disclosed |
| EP-1578723-A4 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | UNIV MICHIGAN STATE (US) | 2006-11-02 | — | — | EP | disclosed |
| EP-1578723-A3 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2005-10-20 | — | — | EP | disclosed |
| EP-1578723-A2 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2003106413-A2 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265451-A1 | Process for the preparation of oxazolidinones and method of use thereof | OXA1L, OTC, ODC1 | GRIK1 3531/4885LMNA 2973/4885ALDH1A1 2186/4885 |
| US-20080146458-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | OXA1L, OGFOD1, CYP51A1 | GRIK1 2079/4885LMNA 2631/4885ALDH1A1 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.