Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.50 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.76 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27534980 | 0.91 | ABAT (0.70) | ABATCA2CA1CA12CA9 | |
| SCHEMBL63123 | 0.87 | — | — | |
| SCHEMBL20696075 | 0.85 | ABAT (0.94) | ABATCA2TAAR1KDM4EALDH1A1 | |
| SCHEMBL27558427 | 0.85 | — | — | |
| Water SCHEMBL8381326 | 0.85 | ABAT (0.94) | ABATCA2TAAR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL920435 | 0.85 | ABAT (0.94) | ABATTAAR1KDM4EALDH1A1SLC6A2 | |
| Bromide SCHEMBL3539884 | 0.85 | ABAT (0.94) | ABATCA2TAAR1KDM4EALDH1A1 | |
| SCHEMBL27827976 | 0.85 | ABAT (0.67) | ABATCA2CA1CA12CA9 | |
| Tyramine SCHEMBL236651 | 0.82 | TAAR1 (0.78) | ABATCA2CA1CA12CA9 | |
| Tyramine SCHEMBL7044901 | 0.82 | TAAR1 (0.78) | ABATCA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534565-A | DICYANDIAMIDE DERIVATIVES FOR LAMINATES | ALLIEDSIGNAL INC. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0540644-B1 | SUBSTITUTED CYANOGUANIDINES AS CURING AGENTS FOR EPOXY RESINS | ALLIED SIGNAL INC (US) | 1995-08-23 | — | — | EP | disclosed |
| US-5387656-A | Soluble in various solvents; do not require the use of undesirable solvents necessary with cyanoguanidine itself | ALLIEDSIGNAL INC. (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1994014866-A1 | SOLVENT FREE EPOXY RESIN COMPOSITIONS | ALLIEDSIGNAL, INC. (US) | 1994-07-07 | — | — | WO | disclosed |
| EP-0540644-A1 | SUBSTITUTED CYANOGUANIDINES AS CURING AGENTS FOR EPOXY RESINS. | ALLIED SIGNAL INC (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001726-A1 | SUBSTITUTED CYANOGUANIDINES AS CURING AGENTS FOR EPOXY RESINS | ALLIED-SIGNAL INC. (US) | 1992-02-06 | — | — | WO | disclosed |