Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067567 | 0.89 | THRB (0.41) | TSHRALDH1A1THRBSMPD1CHRM1 | |
| SCHEMBL9067673 | 0.86 | TSHR (0.41) | TSHRALDH1A1THRBSMPD1GALR3 | |
| SCHEMBL9068417 | 0.86 | TSHR (0.44) | TSHRALDH1A1THRBSMPD1GALR3 | |
| SCHEMBL28151164 | 0.83 | TSHR (0.37) | TSHRALDH1A1SMPD1CHRM2CHRM4 | |
| SCHEMBL27624717 | 0.78 | BTN3A1 (0.33) | TSHRSMPD1CHRM2CHRM4CHRM1 | |
| SCHEMBL6276269 | 0.78 | THRB (0.39) | TSHRALDH1A1THRBGALR3MAPT | |
| SCHEMBL176508 | 0.75 | THRB (0.38) | TSHRALDH1A1THRBCHRM2CHRM4 | |
| SCHEMBL27557630 | 0.74 | SMPD1 (0.43) | TSHRSMPD1CHRM2CHRM4CHRM1 | |
| SCHEMBL541861 | 0.73 | TSHR (0.42) | TSHRALDH1A1THRBSMPD1GALR3 | |
| Methacrylic Acid SCHEMBL3884365 | 0.72 | SMN1; SMN2 (0.36) | TSHRALDH1A1THRBGALR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537972-B1 | Treating solution for contact lenses | NOF CORP (JP) | 1996-07-10 | — | — | EP | claimed |
| US-5461433-A | Cleaning contact lens by immersing in solution containing copolymer where one of the monomers contains phsophate and tertiary ammonium groups | NOF CORPORATION (JP) | 1995-10-24 | — | — | US | claimed |
| EP-0537972-A1 | Treating solution for contact lenses | NOF CORPORATION (JP) | 1993-04-21 | — | — | EP | claimed |
| EP-0537972-B1 | Treating solution for contact lenses | NOF CORP (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5461433-A | Cleaning contact lens by immersing in solution containing copolymer where one of the monomers contains phsophate and tertiary ammonium groups | NOF CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0537972-A1 | Treating solution for contact lenses | NOF CORPORATION (JP) | 1993-04-21 | — | — | EP | disclosed |