Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067673 | 0.97 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9067567 | 0.92 | THRB (0.41) | TSHRTHRBSMPD1ALDH1A1GALR3 | |
| SCHEMBL9067328 | 0.86 | TSHR (0.38) | TSHRTHRBSMPD1ALDH1A1GALR3 | |
| SCHEMBL6276269 | 0.82 | THRB (0.39) | TSHRTHRBALDH1A1GALR3MAPT | |
| SCHEMBL541372 | 0.82 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28062034 | 0.81 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541106 | 0.81 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541808 | 0.81 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541861 | 0.80 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27624717 | 0.80 | BTN3A1 (0.33) | TSHRSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537972-B1 | Treating solution for contact lenses | NOF CORP (JP) | 1996-07-10 | — | — | EP | claimed |
| US-5461433-A | Cleaning contact lens by immersing in solution containing copolymer where one of the monomers contains phsophate and tertiary ammonium groups | NOF CORPORATION (JP) | 1995-10-24 | — | — | US | claimed |
| EP-0537972-A1 | Treating solution for contact lenses | NOF CORPORATION (JP) | 1993-04-21 | — | — | EP | claimed |
| EP-0537972-B1 | Treating solution for contact lenses | NOF CORP (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5461433-A | Cleaning contact lens by immersing in solution containing copolymer where one of the monomers contains phsophate and tertiary ammonium groups | NOF CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0537972-A1 | Treating solution for contact lenses | NOF CORPORATION (JP) | 1993-04-21 | — | — | EP | disclosed |