Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440997 | 0.95 | — | — | |
| SCHEMBL30753573 | 0.95 | — | — | |
| SCHEMBL441399 | 0.81 | — | — | |
| SCHEMBL4308047 | 0.81 | MEN1 (0.50) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL9633934 | 0.81 | MEN1 (0.50) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL274489 | 0.81 | LMNA (0.42) | ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL9619109 | 0.79 | LMNA (0.43) | ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL15384198 | 0.78 | SMN1; SMN2 (0.32) | ALDH1A1LMNATSHR | |
| SCHEMBL11021303 | 0.78 | LMNA (0.37) | LMNA | |
| Alcohol SCHEMBL2204414 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465835-B1 | Anionic living polymers, their derivatives and composition comprising them | DAINIPPON INK & CHEMICALS (JP) | 1996-05-01 | — | — | EP | disclosed |