SCHEMBL274489

SCHEMBL274489

CC(OCCO)OCCO

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
TSHR P16473 3/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9619109 0.91 LMNA (0.43) LMNATSHRMAPK1ALDH1A1MEN1
SCHEMBL1482928 0.89
SCHEMBL6700786 0.88 TSHR (0.35) LMNATSHRMAPK1ALDH1A1MEN1
SCHEMBL10960866 0.87 LMNA (0.33) LMNATSHRMAPK1ALDH1A1
SCHEMBL1029553 0.87 LMNA (0.33) LMNATSHRMAPK1ALDH1A1
SCHEMBL30753573 0.85
SCHEMBL440997 0.85
SCHEMBL8634083 0.85 ALDH1A1 (0.33) LMNATSHRMAPK1ALDH1A1MEN1
SCHEMBL2928095 0.84 LMNA (0.32) LMNA
SCHEMBL1482890 0.84 TSHR (0.52) LMNATSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11872318-B2 Nanocrystals, compositions, and methods that aid particle transport in mucus THE JOHNS HOPKINS UNIVERSITY (US) 2024-01-16 US disclosed
US-20230201111-A1 COMPOSITIONS AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS THE JOHNS HOPKINS UNIVERSITY 2023-06-29 US disclosed
EP-4194438-A1 ACETAL-BASED COMPOUND, ACETAL-BASED PREPOLYMER, ACETAL-BASED POLYMER, AND PHOTORESIST COMPOSITION COMPRISING THE SAME Samsung Electronics Co., Ltd. (KR) 2023-06-14 EP disclosed
US-20230174471-A1 ACETAL-BASED COMPOUND, ACETAL-BASED PREPOLYMER, ACETAL-BASED POLYMER, AND PHOTORESIST COMPOSITION COMPRISING THE SAME INHA INDUSTRY PARTNERSHIP INSTITUTE (KR) 2023-06-08 US disclosed
US-20230174471-A1 ACETAL-BASED COMPOUND, ACETAL-BASED PREPOLYMER, ACETAL-BASED POLYMER, AND PHOTORESIST COMPOSITION COMPRISING THE SAME INHA INDUSTRY PARTNERSHIP INSTITUTE (KR) 2023-06-08 US disclosed
US-20230157965-A1 NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS THE JOHNS HOPKINS UNIVERSITY 2023-05-25 US disclosed
US-11642317-B2 Nanocrystals, compositions, and methods that aid particle transport in mucus THE JOHNS HOPKINS UNIVERSITY (US) 2023-05-09 US disclosed
US-20180064641-A1 COMPOSITIONS AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS THE JOHNS HOPKINS UNIVERSITY 2018-03-08 US disclosed
US-9827191-B2 Compositions and methods for ophthalmic and/or other applications THE JOHNS HOPKINS UNIVERSITY (US) 2017-11-28 US disclosed
US-20170266120-A1 NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS THE JOHNS HOPKINS UNIVERSITY 2017-09-21 US disclosed
US-20090099320-A1 LASER-DECOMPOSABLE RESIN COMPOSITION AND LASER-DECOMPOSABLE PATTERN-FORMING MATERIAL AND FLEXOGRAPHIC PRINTING PLATE PRECURSOR OF LASER ENGRAVING TYPE USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-16 US disclosed
US-20080057437-A1 heat-decomposable cured polyurethane having an aromatic group is directly connected to a urethane bond; high sensitivity to easily form a pattern FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
US-20080057437-A1 heat-decomposable cured polyurethane having an aromatic group is directly connected to a urethane bond; high sensitivity to easily form a pattern FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
US-20040181099-A1 Aromatic ethers and process for producing aromatic ethers NIPPON SHOKUBAI CO., LTD. (JP) 2004-09-16 US disclosed
EP-1148784-A1 WEED CONTROL AVENTIS AGRICULTURE LTD. (GB) 2001-10-31 EP disclosed
WO-2000045637-A1 WEED CONTROL AVENTIS AGRICULTURE LIMITED (GB) 2000-08-10 WO disclosed
EP-0526740-B1 High strength polyester yarn and method for its production HOECHST AG (DE) 1998-03-25 EP disclosed
US-5464694-A High strength, modulus, dyeability, enhanced shrinkage HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-07 US disclosed
EP-0587022-A2 Fully oriented polyester yarn and process for its production HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-16 EP disclosed
EP-0526740-A2 High strength polyester yarn and method for its production HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180064641-A1 COMPOSITIONS AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS MUC1, PDE6C, STRA6 LMNA 1275/4885TSHR 1911/4885MAPK1 4157/4885
US-20230157965-A1 NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS MUC1, SLC35A1, EPCAM LMNA 1966/4885TSHR 2589/4885MAPK1 4000/4885
US-20170266120-A1 NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS MUC1, SLC35A1, EPCAM LMNA 1966/4885TSHR 2589/4885MAPK1 4000/4885
US-11872318-B2 Nanocrystals, compositions, and methods that aid particle transport in mucus MUC1, SLC35A1, EPCAM LMNA 1966/4885TSHR 2589/4885MAPK1 4000/4885
US-20230201111-A1 COMPOSITIONS AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS MUC1, PDE6C, STRA6 LMNA 1275/4885TSHR 1911/4885MAPK1 4157/4885
US-20230174471-A1 ACETAL-BASED COMPOUND, ACETAL-BASED PREPOLYMER, ACETAL-BASED POLYMER, AND PHOTORESIST COMPOSITION COMPRISING THE SAME PARP10, ADCY10, APRT LMNA 777/4885TSHR 4815/4885MAPK1 1970/4885
US-20040181099-A1 Aromatic ethers and process for producing aromatic ethers XDH, FTO, CYP4F8 LMNA 4621/4885TSHR 1258/4885MAPK1 2000/4885
US-11642317-B2 Nanocrystals, compositions, and methods that aid particle transport in mucus MUC1, SLC35A1, EPCAM LMNA 1966/4885TSHR 2589/4885MAPK1 4000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.