Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9067569 | 0.94 | ACHE (0.50) | ACHETDP1ALDH1A1CA7CA1 | |
| Hydrochloric Acid SCHEMBL1955169 | 0.94 | ACHE (0.50) | ACHETDP1ALDH1A1CA7CA1 | |
| SCHEMBL8375414 | 0.86 | ACHE (0.42) | ACHETDP1ALDH1A1CA7CA1 | |
| SCHEMBL8376840 | 0.86 | ACHE (0.42) | ACHETDP1ALDH1A1CA7CA1 | |
| SCHEMBL8372278 | 0.86 | ACHE (0.42) | ACHETDP1ALDH1A1CA7CA1 | |
| SCHEMBL8606184 | 0.86 | ACHE (0.42) | ACHETDP1ALDH1A1CA7CA1 | |
| Phosphoric Acid SCHEMBL9067659 | 0.82 | HPGD (0.41) | ACHETDP1ALDH1A1CA7CA1 | |
| Acetic Acid SCHEMBL9068172 | 0.80 | MAPT (0.42) | ACHETDP1ALDH1A1CA1MAPT | |
| Bromide SCHEMBL2494995 | 0.78 | ACHE (0.53) | ACHETDP1ALDH1A1CA7CA1 | |
| Bromide SCHEMBL9179274 | 0.75 | ACHE (0.50) | ACHETDP1ALDH1A1CA7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534565-A | DICYANDIAMIDE DERIVATIVES FOR LAMINATES | ALLIEDSIGNAL INC. (US) | 1996-07-09 | — | — | US | disclosed |
| WO-1994014866-A1 | SOLVENT FREE EPOXY RESIN COMPOSITIONS | ALLIEDSIGNAL, INC. (US) | 1994-07-07 | — | — | WO | disclosed |