Phosphoric Acid

SCHEMBL9067659

Cc1ccc([P+](C)(c2ccc(C)cc2)c2ccc(C)cc2)cc1.Cc1ccc([P+](C)(c2ccc(C)cc2)c2ccc(C)cc2)cc1.Cc1ccc([P+](C)(c2ccc(C)cc2)c2ccc(C)cc2)cc1.O=P([O-])([O-])[O-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	HPGD	P15428	1/20	0.41

▸	TSHR	P16473	3/20	0.39

▸	LMNA	P02545	2/20	0.39

▸	ACHE	P22303	2/20	0.38

▸	TDP1	Q9NUW8	1/20	0.38

▸	CYP3A4	P08684	2/20	0.38

▸	MEN1	O00255	1/20	0.38

▸	KMT2A	Q03164	1/20	0.38

▸	GAA	P10253	2/20	0.37

▸	CA12	O43570	3/20	0.36

▸	CA1	P00915	2/20	0.36

▸	MMP8	P22894	2/20	0.36

▸	CA9	Q16790	2/20	0.36

▸	MMP2	P08253	2/20	0.36

▸	CA14	Q9ULX7	1/20	0.36

▸	GBA1	P04062	1/20	0.36

▸	FDFT1	P37268	1/20	0.36

▸	ALDH1A1	P00352	3/20	0.35

▸	CYP2C9	P11712	1/20	0.35

▸	CYP2C19	P33261	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Iodide SCHEMBL9067569	0.82	ACHE (0.50)	TSHRLMNAACHETDP1CA1
Bromide SCHEMBL9067693	0.82	ACHE (0.50)	TSHRLMNAACHETDP1CA1
Hydrochloric Acid SCHEMBL1955169	0.82	ACHE (0.50)	TSHRLMNAACHETDP1CA1
Acetic Acid SCHEMBL9068172	0.79	MAPT (0.42)	HPGDLMNAACHETDP1MEN1
P-Xylene SCHEMBL10690560	0.79	ACHE (0.53)	HPGDTSHRLMNAACHETDP1
Phosphoric Acid SCHEMBL8972960	0.78	ALDH1A1 (0.40)	TDP1MEN1KMT2AGAAFDFT1
P-Xylene SCHEMBL28237278	0.76	LMNA (0.52)	HPGDTSHRLMNAACHETDP1
Phosphoric Acid SCHEMBL7193240	0.76	LMNA (0.40)	HPGDTSHRLMNAACHETDP1
SCHEMBL9633418	0.76	GAA (0.48)	TSHRLMNATDP1CYP3A4MEN1
SCHEMBL8375414	0.75	ACHE (0.42)	TSHRLMNAACHETDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5534565-A	DICYANDIAMIDE DERIVATIVES FOR LAMINATES	ALLIEDSIGNAL INC. (US)	1996-07-09	—	—	US	disclosed
WO-1994014866-A1	SOLVENT FREE EPOXY RESIN COMPOSITIONS	ALLIEDSIGNAL, INC. (US)	1994-07-07	—	—	WO	disclosed