Imidazole

Imidazole

SCHEMBL9067808

OB(O)F.c1c[nH]cn1.c1c[nH]cn1

nearest known ligand 0.68

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.68
FKBP5 Q13451 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL29273383 1.00 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL487115 1.00 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL5694374 1.00 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL2902748 0.89
Imidazole SCHEMBL4303384 0.89 ALDH1A1 (0.77) ALDH1A1FKBP5
Imidazole SCHEMBL5159681 0.89
Imidazole SCHEMBL1324864 0.89 ALDH1A1 (0.77) ALDH1A1FKBP5
Imidazole SCHEMBL27603965 0.89 ALDH1A1 (0.77) ALDH1A1FKBP5
Imidazole SCHEMBL156533 0.86
Imidazole SCHEMBL5519550 0.86 ALDH1A1 (0.93) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824491-B Production method of 2,3,4, 4' -tetrahydroxybenzophenone 三峡大学 2022-03-08 CN disclosed
WO-2016156797-A9 PRODUCTION OF FUNCTIONALIZED GRAPHENE THE UNIVERSITY OF MANCHESTER (GB) 2017-08-10 WO disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
US-3941801-A Process for preparing substituted nitroimidazoles MERCK & CO., INC. (US) 1976-03-02 US disclosed