Imidazole

Imidazole

SCHEMBL487115

OB(O)F.OB(O)F.OB(O)F.OB(O)F.c1c[nH]cn1.c1c[nH]cn1.c1c[nH]cn1.c1c[nH]cn1.c1c[nH]cn1.c1c[nH]cn1.c1c[nH]cn1.c1c[nH]cn1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.68
FKBP5 Q13451 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL29273383 1.00 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL9067808 1.00 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL5694374 1.00 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL2902748 0.89
Imidazole SCHEMBL4303384 0.89 ALDH1A1 (0.77) ALDH1A1FKBP5
Imidazole SCHEMBL5159681 0.89
Imidazole SCHEMBL1324864 0.89 ALDH1A1 (0.77) ALDH1A1FKBP5
Imidazole SCHEMBL27603965 0.89 ALDH1A1 (0.77) ALDH1A1FKBP5
Imidazole SCHEMBL156533 0.86
Imidazole SCHEMBL5519550 0.86 ALDH1A1 (0.93) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007006418-A1 IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-01-18 WO claimed
WO-2006131234-A1 COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-14 WO claimed
US-9988339-B2 Nonpolar phase-soluble metathesis catalysts THE TEXAS A&M UNIVERSITY SYSTEM (US) 2018-06-05 US disclosed
US-20160264510-A1 NONPOLAR PHASE-SOLUBLE METATHESIS CATALYSTS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2016-09-15 US disclosed
US-9370770-B2 Nonpolar phase-soluble metathesis catalysts THE TEXAS A&M UNIVERSITY SYSTEM (US) 2016-06-21 US disclosed
US-20150057449-A1 NONPOLAR PHASE-SOLUBLE METATHESIS CATALYSTS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2015-02-26 US disclosed
US-20120232285-A1 Sulfonyl-1,2,4-triazole salts UNIVERSITE DE MONTREAL (CA) 2012-09-13 US disclosed
EP-1947663-B1 ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICE AND ELECTROCHEMICAL DEVICE USING SAME SANYO CHEMICAL IND LTD (JP) 2012-02-01 EP disclosed
US-7919629-B2 Sulphonyl-1,2,4-triazole salts PHOSTECH LITHIUM INC. (CA) 2011-04-05 US disclosed
US-20090292105-A1 SULPHONYL-1,2,4-TRIAZOLE SALTS PHOSTECH LITHIUM INC. (CA) 2009-11-26 US disclosed
US-20090203860-A1 Nonpolar phase-soluble methathesis catalysts NATIONAL SCIENCE FOUNDATION 2009-08-13 US disclosed
US-6621684-B2 Improved stability of electrochemical properties and improved retention of residual voltage, imparted by using an electrolytic solution containing a polymer MATSUSHITA ELECTRIC INSUSTRIAL CO. LTD. (JP) 2003-09-16 US disclosed
US-20020036884-A1 Electric double layer capacitor, electrolytic solution therefore and method for suppressing self-discharge in electronic component MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203860-A1 Nonpolar phase-soluble methathesis catalysts MMAB, HMBS, PEAK1 ALDH1A1 3476/4885FKBP5 598/4885
US-20090292105-A1 SULPHONYL-1,2,4-TRIAZOLE SALTS TST, STS, SQOR ALDH1A1 1639/4885FKBP5 1183/4885
US-20120232285-A1 Sulfonyl-1,2,4-triazole salts STS, TST, FIS1 ALDH1A1 1554/4885FKBP5 2107/4885
US-20150057449-A1 NONPOLAR PHASE-SOLUBLE METATHESIS CATALYSTS SIGMAR1, SUB1, PCBP1 ALDH1A1 3276/4885FKBP5 508/4885
US-20160264510-A1 NONPOLAR PHASE-SOLUBLE METATHESIS CATALYSTS RPA1, SUB1, PCBP1 ALDH1A1 3848/4885FKBP5 948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.