SCHEMBL906789

SCHEMBL906789

O=P(O)(OC1OCO1)OC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.46
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17169179 0.80 NPSR1 (0.61) NPSR1GAA
SCHEMBL4922666 0.75 NPSR1 (0.44) NPSR1GAA
SCHEMBL4749839 0.72 NPSR1 (0.61) NPSR1GAA
SCHEMBL28945078 0.70 NPSR1 (0.55) NPSR1GAA
SCHEMBL4922662 0.69 NPSR1 (0.53) NPSR1GAA
SCHEMBL27600043 0.69 NPSR1 (0.53) NPSR1GAA
SCHEMBL19798472 0.69 NPSR1 (0.69) NPSR1GAA
SCHEMBL906786 0.68 NPSR1 (0.52) NPSR1GAA
SCHEMBL19391909 0.68 NPSR1 (0.52) NPSR1GAA
SCHEMBL4749836 0.67 NPSR1 (0.67) NPSR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2667192-B1 Luminogenic and nonluminogenic multiplex assay PROMEGA CORP (US) 2020-10-07 EP disclosed
US-10745365-B2 Luminogenic and fluorogenic compounds and methods to detect molecules or conditions PROMEGA CORPORATION (US) 2020-08-18 US disclosed
EP-3312292-B1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS PROMEGA CORP (US) 2019-09-25 EP disclosed
EP-1885875-B1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS PROMEGA CORP (US) 2019-05-22 EP disclosed
US-20190031629-A1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2019-01-31 US disclosed
US-10077244-B2 Luminogenic and fluorogenic compounds and methods to detect molecules or conditions PROMEGA CORPORATION (US) 2018-09-18 US disclosed
EP-3312292-A1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS Promega Corporation (US) 2018-04-25 EP disclosed
EP-2778234-B1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS PROMEGA CORP (US) 2017-09-27 EP disclosed
US-20160176830-A1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2016-06-23 US disclosed
EP-2331517-B1 BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS PROMEGA CORP (US) 2016-06-08 EP disclosed
CN-101084437-A Luminescent and non-luminescent multiplex assays PROMEGA CORP (US) 2007-12-05 CN disclosed
US-20070178545-A1 Luminogenic and nonluminogenic multiplex assay JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2007-08-02 US disclosed
WO-2007027653-A1 CELL-BASED LUMINOGENIC AND NONLUMINOGENIC PROTEASOME ASSAYS PROMEGA CORPORATION (US) 2007-03-08 WO disclosed
US-20070048812-A1 Cell-based luminogenic and nonluminogenic proteasome assays PROMEGA CORPORATION 2007-03-01 US disclosed
US-20070015790-A1 Luminogenic and fluorogenic compounds and methods to detect molecules or conditions JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2007-01-18 US disclosed
WO-2006130551-A2 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS PROMEGA CORPORATION (US) 2006-12-07 WO disclosed
EP-1711822-A2 LUMINOGENIC AND NONLUMINOGENIC MULTIPLEX ASSAY PROMEGA CORPORATION (US) 2006-10-18 EP disclosed
WO-2005073722-A2 LUMINOGENIC AND NONLUMINOGENIC MULTIPLEX ASSAY PROMEGA CORPORATION (US) 2005-08-11 WO disclosed
US-20050164321-A1 Colorimetric analysis; kits PROMEGA CORPORATION 2005-07-28 US disclosed
US-5580741-A INCUBATING SAMPLE SOLUTION IN CONTAINER PRECOATED WITH ANTIBODY AND PROTEIN CONJUGATE YIELDS COMPLEXES, THEN REMOVAL AND REACTION WITH CHEMILUMINESCENT REAGENTS FOR MEASUREMENT OF LIGHT INTENSITY, FOR CHLORINATED BIPHENYLS GENERAL ELECTRIC COMPANY (US) 1996-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10745365-B2 Luminogenic and fluorogenic compounds and methods to detect molecules or conditions GLB1, NOD1, PYCARD NPSR1 2510/4885GAA 278/4885
US-10077244-B2 Luminogenic and fluorogenic compounds and methods to detect molecules or conditions GLB1, NOD1, PYCARD NPSR1 2474/4885GAA 277/4885
US-20190031629-A1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS GLB1, NOD1, PYCARD NPSR1 2510/4885GAA 278/4885
US-20160176830-A1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS GLB1, NOD1, PYCARD NPSR1 2474/4885GAA 277/4885
US-20070015790-A1 Luminogenic and fluorogenic compounds and methods to detect molecules or conditions GLB1, NOD1, PYCARD NPSR1 2514/4885GAA 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.