Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPP5C | P53041 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350264 | 0.85 | ALDH1A1 (0.47) | ALDH1A1PPM1BPTPN1PPP1CCATM | |
| SCHEMBL4390371 | 0.78 | PPP5C (0.40) | ALDH1A1PPM1BPTPN1PPP1CCATM | |
| SCHEMBL30603264 | 0.78 | PPP5C (0.40) | ALDH1A1PPM1BPTPN1PPP1CCATM | |
| SCHEMBL9032416 | 0.72 | ALDH1A1 (0.47) | ALDH1A1PPM1BPTPN1PPP1CCATM | |
| SCHEMBL5197172 | 0.71 | ALDH1A1 (0.42) | ALDH1A1PPM1BPTPN1PPP1CCATM | |
| SCHEMBL1664742 | 0.71 | L3MBTL1 (0.56) | ALDH1A1PPARGTSHRTDP1L3MBTL1 | |
| SCHEMBL27783538 | 0.69 | PPM1B (0.71) | ALDH1A1PPM1BPTPN1PPP1CCATM | |
| SCHEMBL11609072 | 0.69 | PPM1B (0.42) | ALDH1A1PPM1BPTPN1PPP1CCATM | |
| SCHEMBL11607831 | 0.68 | PPARG (0.45) | PPM1BPTPN1PPP1CCPPARGTSHR | |
| SCHEMBL14874398 | 0.68 | ALDH1A1 (0.50) | ALDH1A1PPM1BPTPN1PPP1CCATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484874-A | EXHIBITING GOOD MOLD RELEASE, THERMAL STABILITY AND LITTLE DISCOLORATION DURING MOLDING | GE PLASTICS, JAPAN, LTD. (JP) | 1996-01-16 | — | — | US | disclosed |