Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 11/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068232 | 1.00 | SLC2A1 (0.51) | SLC2A1ABCB1DRD2HTR1ATP53 | |
| SCHEMBL8709905 | 0.95 | TP53 (0.49) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8702705 | 0.95 | TP53 (0.49) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8702698 | 0.95 | TP53 (0.49) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8702097 | 0.90 | HTR6 (0.47) | SLC2A1ABCB1TP53CYP3A4ALOX15 | |
| SCHEMBL8703435 | 0.89 | TP53 (0.54) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8707295 | 0.87 | SCN9A (0.47) | SLC2A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL8707388 | 0.86 | EPHA2 (0.49) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8702892 | 0.86 | EPHA2 (0.49) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8703515 | 0.86 | EPHA2 (0.49) | ABCB1DRD2HTR1ATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |