Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 15/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483516 | 1.00 | LSS (0.69) | LSSMAPTALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL9068957 | 0.82 | LSS (1.00) | LSS | |
| SCHEMBL9068958 | 0.82 | LSS (1.00) | LSS | |
| SCHEMBL5035264 | 0.81 | LSS (0.62) | LSSMAPTALDH1A1HSD17B10 | |
| SCHEMBL5039824 | 0.80 | LSS (0.64) | LSSMAPTALDH1A1HSD17B10 | |
| SCHEMBL8479461 | 0.79 | LSS (0.66) | LSSMAPTALDH1A1HSD17B10 | |
| SCHEMBL8484297 | 0.77 | LSS (0.60) | LSS | |
| SCHEMBL5043116 | 0.76 | LSS (0.54) | LSSMAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL8478332 | 0.76 | LSS (0.69) | LSS | |
| SCHEMBL8478334 | 0.76 | LSS (0.69) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778271-A2 | Aminoalkyl-substituted benzo-heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |