Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL9068632 | 1.00 | PAM (0.57) | PAMGPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL11224619 | 1.00 | PAM (0.57) | PAMGPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL3690423 | 1.00 | PAM (0.57) | PAMGPR84PPARGPPARDPPARA | |
| SCHEMBL9580553 | 0.97 | PAM (0.57) | PAMGPR84PPARGPPARDPPARA | |
| SCHEMBL428185 | 0.97 | PAM (0.57) | PAMGPR84PPARGPPARDPPARA | |
| SCHEMBL9580548 | 0.97 | PAM (0.57) | PAMGPR84PPARGPPARDPPARA | |
| SCHEMBL1895871 | 0.93 | DGKA (0.60) | PAMTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL2700380 | 0.93 | DGKA (0.60) | PAMTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL3685763 | 0.93 | DGKA (0.60) | PAMTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL17812653 | 0.93 | DGKA (0.60) | PAMTSHRALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970556-B2 | Methacrylic resin, method of manufacturing methacrylic resin, methacrylic resin composition, shaped article, optical components, and automotive part | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-04-30 | — | — | US | disclosed |
| US-11603441-B2 | Methacrylic resin, shaped article, and optical component or automotive part | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-03-14 | — | — | US | disclosed |
| US-20220195270-A1 | CURABLE SILICONE COMPOSITION, CURED PRODUCT OF SAME, AND METHOD FOR PRODUCING SAME | DOW TORAY CO., LTD. (JP) | 2022-06-23 | — | — | US | disclosed |
| US-20220195269-A1 | CURABLE SILICONE COMPOSITION, CURED PRODUCT OF SAME, AND METHOD FOR PRODUCING SAME | DOW TORAY CO LTD (JP) | 2022-06-23 | — | — | US | disclosed |
| EP-3950846-A1 | CURABLE SILICONE COMPOSITION, CURED PRODUCT OF SAME, AND METHOD FOR PRODUCING SAME | Dow Toray Co., Ltd. (JP) | 2022-02-09 | — | — | EP | disclosed |
| EP-3950844-A1 | CURABLE SILICONE COMPOSITION, CURED PRODUCT OF SAME, AND METHOD FOR PRODUCING SAME | Dow Toray Co., Ltd. (JP) | 2022-02-09 | — | — | EP | disclosed |
| US-20210380742-A1 | METHACRYLIC RESIN, METHOD OF MANUFACTURING METHACRYLIC RESIN, METHACRYLIC RESIN COMPOSITION, SHAPED ARTICLE, OPTICAL COMPONENTS, AND AUTOMOTIVE PART | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-12-09 | — | — | US | disclosed |
| US-20210214477-A1 | METHACRYLIC RESIN, SHAPED ARTICLE, AND OPTICAL COMPONENT OR AUTOMOTIVE PART | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-07-15 | — | — | US | disclosed |
| EP-3822295-A1 | METHACRYLIC RESIN, MOULDED ARTICLE, OPTICAL COMPONENT OR AUTOMOTIVE COMPONENT | Asahi Kasei Kabushiki Kaisha (JP) | 2021-05-19 | — | — | EP | disclosed |
| US-10409067-B2 | Component for head mounted display | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2019-09-10 | — | — | US | disclosed |
| US-20180267315-A1 | COMPONENT FOR HEAD MOUNTED DISPLAY | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-09-20 | — | — | US | disclosed |
| US-9315922-B2 | Polyester-based fiber for artificial hair and hair ornament product including the same | KANEKA CORPORATION (JP) | 2016-04-19 | — | — | US | disclosed |
| US-20150141559-A1 | POLYESTER-BASED FIBER FOR ARTIFICIAL HAIR AND HAIR ORNAMENT PRODUCT INCLUDING THE SAME | KANEKA CORPORATION (JP) | 2015-05-21 | — | — | US | disclosed |
| EP-0563794-B1 | Method of producing vinyl chloride resins | SUMITOMO CHEMICAL CO (JP) | 1996-12-27 | — | — | EP | disclosed |
| US-5508365-A | POLYMERIZING VINYL CHLORIDE AND ETHYLENICALLY UNSATURATED MONOMER IN THE PRESENCE OF A PENTAERYTHRITOL OR DIPENTAERYTHRITOL FATTY ACID ESTER AND A GLYCEROL ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0563794-A1 | Method of producing vinyl chloride resins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |