Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050962 | 0.80 | CYP1A2 (0.63) | MAOAMAOBALDH1A1MAPTCYP1A2 | |
| SCHEMBL772686 | 0.76 | ALDH1A1 (0.59) | MAOAMAOBALDH1A1MAPTMCL1 | |
| SCHEMBL29580615 | 0.74 | PDGFRB (0.51) | MAOAMAOBALDH1A1MAPTCYP1A2 | |
| SCHEMBL28468281 | 0.74 | SIGMAR1 (0.45) | ALDH1A1CYP1A2SNCAPDGFRBFGFR1 | |
| SCHEMBL2253975 | 0.74 | CYP1A2 (0.41) | MAOAMAOBALDH1A1MAPTCYP1A2 | |
| SCHEMBL3894477 | 0.74 | MAPT (0.57) | ALDH1A1MAPTMCL1CYP1A2CYP3A4 | |
| SCHEMBL8386297 | 0.72 | ALDH1A1 (0.39) | MAOAMAOBALDH1A1MAPTMCL1 | |
| SCHEMBL21291914 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTMCL1CYP1A2SNCA | |
| SCHEMBL11241510 | 0.71 | DTYMK (0.46) | MAOAMAOBALDH1A1MAPTMCL1 | |
| SCHEMBL31601810 | 0.71 | AR (0.41) | ALDH1A1CYP1A2SNCAPDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874590-A | Diaminofluorescein derivative | Nagano, Tetsuo (JP) | 1999-02-23 | — | — | US | disclosed |