SCHEMBL9068474

SCHEMBL9068474

C=C(C)C(=O)N[C@H](C(=O)O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.49
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
FPR2 P25090 1/20 0.46
NAALAD2 Q9Y3Q0 1/20 0.45
TGFBR1 P36897 1/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
LMNA P02545 2/20 0.44
MAPK1 P28482 1/20 0.44
LTA4H P09960 1/20 0.43
ANPEP P15144 1/20 0.43
ATM Q13315 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14339911 1.00 HPGD (0.49) HPGDALDH1A1KDM4EFPR2NAALAD2
SCHEMBL14397406 0.85 FPR2 (0.49) HPGDALDH1A1FPR2NAALAD2CA1
SCHEMBL627377 0.85 SRC (0.52) HPGDALDH1A1FPR2NAALAD2CA1
SCHEMBL3376625 0.85 SRC (0.52) HPGDALDH1A1FPR2NAALAD2CA1
SCHEMBL4250144 0.85 SRC (0.52) HPGDALDH1A1FPR2NAALAD2CA1
SCHEMBL5936861 0.83 SRC (0.50) HPGDALDH1A1FPR2NAALAD2CA1
SCHEMBL472254 0.81 ALDH1A1 (0.50) HPGDALDH1A1KDM4ETGFBR1LMNA
SCHEMBL11508098 0.81 ALDH1A1 (0.50) HPGDALDH1A1KDM4ETGFBR1KMT2A
SCHEMBL1629333 0.80 KDM4E (0.55) HPGDALDH1A1KDM4ELMNAHDAC6
SCHEMBL1823688 0.80 HPGD (0.50) HPGDALDH1A1KDM4ETGFBR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5549807-A Thermoplastic composites formed by electropolymerization of N-substituted methacrylamide monomers THE UNIVERSITY OF CONNECTICUT (US) 1996-08-27 US claimed
US-5238542-A Onto electrically conductive filler THE UNIVERSITY OF CONNECTICUT (US) 1993-08-24 US claimed
US-5466357-A THERMOPLASTIC MATRIX PREPREG COMPOSITE PRODUCT THE UNIVERSITY OF CONNECTICUT (US) 1995-11-14 US disclosed