Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068550 | 1.00 | POLB (0.57) | POLBSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL11754467 | 0.86 | ALDH1A1 (0.50) | POLBSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL22035957 | 0.83 | POLB (0.56) | POLBSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1533473 | 0.82 | POLB (0.55) | POLBSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL25248841 | 0.82 | POLB (0.54) | POLBSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9231726 | 0.82 | POLB (0.56) | POLBLMNAGAAMEN1KMT2A | |
| SCHEMBL510548 | 0.82 | ALDH1A1 (0.56) | POLBSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7040363 | 0.82 | ESR1 (0.47) | POLBALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL7705115 | 0.82 | ALDH1A1 (0.56) | POLBSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL305061 | 0.81 | CYP2C19 (0.57) | POLBSMN1; SMN2ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587510-A | ASYMMETRICAL HYDROGENATION USING RUTHENIUM-PHOPSHINE COMPLEX AS CATALYSTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-12-24 | — | — | US | disclosed |