Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705115 | 1.00 | ALDH1A1 (0.56) | ALDH1A1POLBAKR1C3AKR1C2MEN1 | |
| Toluene SCHEMBL8901851 | 0.94 | ALDH1A1 (0.59) | ALDH1A1POLBAKR1C3AKR1C2MEN1 | |
| SCHEMBL1574429 | 0.91 | AKR1C3 (0.58) | ALDH1A1POLBAKR1C3AKR1C2PTGS1 | |
| Toluene SCHEMBL28260671 | 0.88 | ALDH1A1 (0.61) | ALDH1A1POLBAKR1C3AKR1C2MEN1 | |
| SCHEMBL22035957 | 0.85 | POLB (0.56) | ALDH1A1POLBAKR1C3AKR1C2MEN1 | |
| SCHEMBL4269790 | 0.84 | POLB (0.51) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9872058 | 0.84 | ALDH1A1 (0.53) | ALDH1A1POLBAKR1C3AKR1C2MEN1 | |
| SCHEMBL25248841 | 0.83 | POLB (0.54) | ALDH1A1POLBAKR1C3AKR1C2MEN1 | |
| SCHEMBL31558611 | 0.83 | ALDH1A1 (0.51) | ALDH1A1POLBAKR1C3AKR1C2MEN1 | |
| SCHEMBL819392 | 0.83 | LMNA (0.61) | ALDH1A1AKR1C3AKR1C2PTGS1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3133903-A | — | — | None | — | — | JP | disclosed |
| US-12336991-B2 | Factor XIIA inhibitors | UNIVERSITY OF LEEDS (GB) | 2025-06-24 | — | — | US | disclosed |
| EP-4559918-A2 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | Genzyme Corporation (US) | 2025-05-28 | — | — | EP | disclosed |
| EP-3673906-B1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORP (US) | 2025-05-14 | — | — | EP | disclosed |
| CN-118541359-A | Inhibitors of molluscum contagiosum infection and methods of use thereof | 宾夕法尼亚大学董事会 | 2024-08-23 | — | — | CN | disclosed |
| EP-4387950-A1 | USE OF 1-(4- TERT- BUTYL CYCLOHEXYL) PROPYL ACETATE AS AROMA INGREDIENT | BASF SE (DE) | 2024-06-26 | — | — | EP | disclosed |
| CN-117915918-A | Soluble adenylate cyclase (sAC) inhibitors and uses thereof | 康奈尔大学 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023021063-A1 | USE OF 1-(4- TERT- BUTYL CYCLOHEXYL) PROPYL ACETATE AS AROMA INGREDIENT | BASF SE (DE) | 2023-02-23 | — | — | WO | disclosed |
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2022-09-29 | — | — | US | disclosed |
| CN-113573742-A | Novel tumor antigen binding agents and uses thereof | 同位素技术慕尼黑公司 | 2021-10-29 | — | — | CN | disclosed |
| US-4054572-A | Hexahydro pyridine [1,2d] dibenza [b,f] (1,4)-diazepines | AKZONA INCORPORATED (US) | 1977-10-18 | — | — | US | disclosed |
| US-4052387-A | METHOD OF PREPARATION OF 3-METHYLENECEPHAMS | ELI LILLY AND COMPANY (US) | 1977-10-04 | — | — | US | disclosed |
| US-4016161-A | Amino-substituted 1,2,3,4,10,146-hexahydro-pyridino[1,2-a]dibenzo[c,f]azepines | AKZONA INCORPORATED (US) | 1977-04-05 | — | — | US | disclosed |
| US-4013682-A | N-HYDROXY-AMIDINE COMPOUNDS | AKZONA INCORPORATED (US) | 1977-03-22 | — | — | US | disclosed |
| US-4012380-A | 7-Acylamino-3-acyl-2(or 3)cephems | ELI LILLY AND COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-3978126-A | N-HYDROXY-AMIDINE COMPOUNDS | AKZONA INCORPORATED (US) | 1976-08-31 | — | — | US | disclosed |
| US-3972906-A | Novel - 11-substituted steroids of the estrane series | AKZONA INCORPORATED (US) | 1976-08-03 | — | — | US | disclosed |
| US-3968124-A | Process for preparing phenyl-acetic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-07-06 | — | — | US | disclosed |
| US-3966723-A | 1,2,3,4,10,14B-Hexahydro-pyridino[1,2-a]-dibenzo[c,f]-azepine | AKZONA INCORPORATED (US) | 1976-06-29 | — | — | US | disclosed |
| US-3965114-A | Imidazolidine derivatives | AKZONA INCORPORATED (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F12 | ALDH1A1 2363/4885POLB 2428/4885AKR1C3 644/4885 |
| US-12336991-B2 | Factor XIIA inhibitors | F11, F13B, F12 | ALDH1A1 2363/4885POLB 2428/4885AKR1C3 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.