Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490167 | 0.77 | HTR2A (0.48) | KMT2AMEN1GAAHTR2AGPR3 | |
| SCHEMBL1304934 | 0.77 | HTR2A (0.48) | KMT2AMEN1GAAHTR2AGPR3 | |
| SCHEMBL4022049 | 0.75 | HTR2A (0.46) | KMT2AMEN1GAAHTR2AGPR3 | |
| SCHEMBL982364 | 0.75 | HTR2A (0.46) | KMT2AMEN1GAAHTR2AGPR3 | |
| SCHEMBL1667065 | 0.74 | HTR2A (0.41) | KMT2AMEN1GAAHTR2AGPR3 | |
| SCHEMBL8840921 | 0.73 | ALDH1A1 (0.48) | KMT2AMEN1GAAHTR2AGPR3 | |
| SCHEMBL382854 | 0.73 | MEN1 (0.46) | KMT2AMEN1GAAHTR2AGPR3 | |
| SCHEMBL19326642 | 0.73 | MEN1 (0.38) | KMT2AMEN1GAAHTR2AHDAC3 | |
| SCHEMBL8339930 | 0.73 | HPGD (0.46) | KMT2AMEN1GAAHTR2AGPR3 | |
| SCHEMBL6237100 | 0.73 | ALDH1A1 (0.46) | KMT2AMEN1GAAHTR2AGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589556-A | METALLOCENE, ALUMOXANE | FINA TECHNOLOGY, INC. (US) | 1996-12-31 | — | — | US | claimed |
| US-5589556-A | METALLOCENE, ALUMOXANE | FINA TECHNOLOGY, INC. (US) | 1996-12-31 | — | — | US | disclosed |
| US-5304523-A | Stereorigid metallocene containing transition metal | FINA TECHNOLOGY, INC. (US) | 1994-04-19 | — | — | US | disclosed |