SCHEMBL6237100

SCHEMBL6237100

Oc1cccc(C2c3ccccc3-c3ccccc32)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
HPGD P15428 4/20 0.46
HSD17B10 Q99714 4/20 0.46
ALOX15 P16050 4/20 0.46
LMNA P02545 3/20 0.46
EGFR P00533 2/20 0.46
CA2 P00918 2/20 0.46
FYN P06241 2/20 0.46
MMP9 P14780 2/20 0.46
RECQL P46063 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ADAMTS4 O75173 1/20 0.46
CA1 P00915 1/20 0.46
MMP2 P08253 1/20 0.46
MMP8 P22894 1/20 0.46
CA6 P23280 1/20 0.46
CDK2 P24941 1/20 0.46
MMP12 P39900 1/20 0.46
ADAMTS5 Q9UNA0 1/20 0.46
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8339930 0.91 HPGD (0.46) ALDH1A1HPGDHSD17B10ALOX15LMNA
SCHEMBL382854 0.84 MEN1 (0.46) ALDH1A1HPGDHSD17B10ALOX15LMNA
SCHEMBL8840921 0.84 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10ALOX15LMNA
SCHEMBL9099683 0.78 PPIA (0.41) ALDH1A1HPGDHSD17B10ALOX15LMNA
SCHEMBL3224110 0.76 PTPN22 (0.48) ALDH1A1HPGDHSD17B10TDP1KDM4E
SCHEMBL9161966 0.76 CA12 (0.57) ALDH1A1HPGDCA2CA1CA6
SCHEMBL442713 0.74 MEN1 (0.47) ALDH1A1HPGDHSD17B10ALOX15MEN1
SCHEMBL9068624 0.73 KMT2A (0.50) CA2CA1MEN1GAAKMT2A
SCHEMBL1261847 0.72 MEN1 (0.45) ALDH1A1HPGDHSD17B10ALOX15LMNA
SCHEMBL5070105 0.72 PPIA (0.45) ALDH1A1HPGDHSD17B10ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6953653-B2 Fluoropolymer compositions, optical devices, and methods for fabricating optical devices CLEMSON UNIVERSITY (US) 2005-10-11 US disclosed
EP-1138714-B1 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL CO (JP) 2005-02-23 EP disclosed
US-6777070-B1 HARD COATING IS A COPOLYMER OF A FLUORENE ACRYLATE AND A URETHANE ACRYLATE; DISPLAYS; HIGH REFRACTIVE INDEX AN DURABLE TOMOEGAWA PAPER CO., LTD. (JP) 2004-08-17 US disclosed
US-6696534-B2 FOR OPTICAL WAVEGUIDES AND OTHER DEVICES USING REFRACTIVE PROPERTIES CLEMSON UNIVERSITY 2004-02-24 US disclosed
US-20040033047-A1 Fluoropolymer compositions, optical devices, and methods for fabricating optical devices CLEMSON UNIVERSITY 2004-02-19 US disclosed
US-6689855-B2 SUITABLE PROPERTIES FOR OPTICAL WAVEGUIDES PREPARED USING PHOTORESISTS; FOR MICROMOLDING AND PHOTOLITHOGRAPHIC PRINTING CLEMSON UNIVERSITY 2004-02-10 US disclosed
US-6649715-B1 Casting and curing mixtures of halogenated carbocyclic ethers on silicon masters to form thermoplastic or thermosetting resins having patterns, used as waveguides CLEMSON UNIVERSITY 2003-11-18 US disclosed
US-20030050416-A1 Diffraction devices and methods CLEMSON UNIVERSITY 2003-03-13 US disclosed
WO-2003021313-A1 FLUOROPOLYMER COMPOSITIONS, OPTICAL DEVICES, AND METHODS FOR FABRICATING OPTICAL DEVICES CLEMSON UNIVERSITY (US) 2003-03-13 WO disclosed
US-20030023014-A1 Random copolymer compositions SMITH DENNIS W (US) 2003-01-30 US disclosed
EP-0877972-B1 FABRICATION OF COVERED MICROCHANNELS UNIV WASHINGTON (US) 2002-04-17 EP disclosed
WO-2002000739-A1 FLUOROPOLYMERS AND METHODS OF APPLYING FLUOROPOLYMERS IN MOLDING PROCESSES CLEMSON UNIVERSITY (US) 2002-01-03 WO disclosed
EP-0598552-B1 Cross-linkable polymeric composition SOLA INT HOLDINGS (AU) 1999-06-02 EP disclosed
EP-0877972-A1 COVERED MICROCHANNELS AND THE MICROFABRICATION THEREOF University of Washington (US) 1998-11-18 EP disclosed
US-5783452-A Covered microchannels and the microfabrication thereof UNIVERSITY OF WASHINGTON (US) 1998-07-21 US disclosed
WO-1997028490-A1 COVERED MICROCHANNELS AND THE MICROFABRICATION THEREOF UNIVERSITY OF WASHINGTON (US) 1997-08-07 WO disclosed
EP-0684972-A1 BLACK-COLORED, LASER-WRITABLE BLENDS OF CARBONATE POLYMER AND POLYESTER THE DOW CHEMICAL COMPANY (US) 1995-12-06 EP disclosed
WO-1994019408-A1 BLACK-COLORED, LASER-WRITABLE BLENDS OF CARBONATE POLYMER AND POLYESTER THE DOW CHEMICAL COMPANY (US) 1994-09-01 WO disclosed
US-5300350-A Incorporating a fatty acid metal salt and carbon black THE DOW CHEMICAL COMPANY (US) 1994-04-05 US disclosed