Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | IAPP | P10997 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1698715 | 0.89 | GABRA1 (0.54) | ALDH1A1TDP1KDM4EMEN1POLB | |
| SCHEMBL6777956 | 0.83 | HTR2A (0.45) | ALDH1A1TDP1KDM4EMEN1POLB | |
| SCHEMBL29354255 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TDP1KDM4EMEN1POLB | |
| SCHEMBL116610 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TDP1KDM4EMEN1POLB | |
| SCHEMBL8045012 | 0.81 | HTR2A (0.50) | ALDH1A1TDP1KDM4EMEN1POLB | |
| SCHEMBL796968 | 0.81 | HTR2A (0.50) | ALDH1A1TDP1KDM4EMEN1POLB | |
| SCHEMBL8045011 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TDP1KDM4EMEN1POLB | |
| SCHEMBL29368415 | 0.81 | HTR2A (0.50) | ALDH1A1TDP1KDM4EMEN1POLB | |
| SCHEMBL28611072 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1KDM4EMEN1POLB | |
| Hydrochloric Acid SCHEMBL6915484 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1KDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563180-A | REACTING POLYISOCYANATE, POLYESTERPOLYOL IN THE PRESENCE OF BLOWING AGENT AND CATALYST; CLOSED CELL RIGID FOAM | THE CELOTEX CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| US-5470889-A | Fire resistant roofing material | THE CELOTEX CORPORATION (US) | 1995-11-28 | — | — | US | disclosed |
| US-5405884-A | Mixture of alkali or alkaline earth metal carboxylic salt, tertiary amine and quaternary ammonium carboxylic salt | THE CELOTEX CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5308883-A | Rigid closed-cell foam from polyisocyanate and polyesterpolyol and blowing agent with catalyst | THE CELOTEX CORPORATION (US) | 1994-05-03 | — | — | US | disclosed |
| US-4710521-A | SALT OF CARBOXYLIC ACIDS AND TERTIARY AMINES | THE CELOTEX CORPORATION (US) | 1987-12-01 | — | — | US | disclosed |