Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10549886 | 0.85 | CPB2 (0.44) | CPB2MMEACEALDH1A1 | |
| SCHEMBL489084 | 0.82 | CPB2 (0.51) | CPB2KISS1RSLC1A3SLC1A2MME | |
| SCHEMBL489085 | 0.82 | CPB2 (0.51) | CPB2KISS1RSLC1A3SLC1A2MME | |
| SCHEMBL1708851 | 0.80 | CPB2 (0.42) | CPB2KISS1RSLC1A3SLC1A2MME | |
| SCHEMBL10553705 | 0.79 | CPB2 (0.41) | CPB2MMEACEALDH1A1 | |
| SCHEMBL7341626 | 0.79 | CPB2 (0.41) | CPB2SLC1A3SLC1A2MMEACE | |
| SCHEMBL9743096 | 0.74 | MME (0.44) | MMEACE | |
| SCHEMBL607225 | 0.74 | MME (0.44) | MMEACE | |
| SCHEMBL5295104 | 0.74 | MME (0.44) | MMEACE | |
| SCHEMBL11438740 | 0.73 | CPB2 (0.37) | CPB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0361365-A1 | Aminobenzoic and aminocyclohexane-carboylic acid compounds, compositions, and their method of use | E.R. SQUIBB & SONS, INC. (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0086757-A1 | Derivatives of alpha or beta-mercaptopropionylamidoacetic acids, processes for their preparation and the therapeutic compositions which include them as active principles | Farmatis S.r.l. (IT) | 1983-08-24 | — | — | EP | disclosed |
| EP-0021766-B1 | INHIBITORS OF MAMMALIAN COLLAGENASE | E.R. Squibb & Sons, Inc. (US) | 1983-02-09 | — | — | EP | disclosed |
| US-4297275-A | Inhibitors of mammalian collagenase | E. R. SQUIBB & SONS, INC. (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0021766-A2 | Inhibitors of mammalian collagenase | E.R. Squibb & Sons, Inc. (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4235885-A | Inhibitors of mammalian collagenase | E. R. SQUIBB & SONS, INC. (US) | 1980-11-25 | — | — | US | disclosed |