Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.58 |
| ▸ | ACE | P12821 | 7/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067110 | 0.84 | MME (0.67) | MMEACEECE1 | |
| SCHEMBL4371284 | 0.81 | MME (0.72) | MMEACE | |
| SCHEMBL11487873 | 0.79 | MME (0.55) | MMEACECPA1ACE2ECE1 | |
| SCHEMBL2871612 | 0.78 | MME (0.68) | MMEACEECE1 | |
| SCHEMBL2977232 | 0.78 | SLC1A3 (0.56) | MMECPA1 | |
| SCHEMBL841290 | 0.78 | SLC1A3 (0.56) | MMECPA1 | |
| SCHEMBL2967728 | 0.78 | SLC1A3 (0.56) | MMECPA1 | |
| SCHEMBL4288816 | 0.77 | MMP2 (0.63) | MMEECE1 | |
| SCHEMBL11483997 | 0.77 | MME (0.54) | MMEACECPA1ACE2ECE1 | |
| SCHEMBL23408778 | 0.76 | ACE (0.48) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |