Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | CPA3 | P15088 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 7/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728572 | 1.00 | FOLH1 (0.51) | FOLH1PTGESALOX5PPARGCPA3 | |
| SCHEMBL8666117 | 0.85 | EPHX2 (0.54) | CPA3CYP1A2LTA4HMMEACE | |
| SCHEMBL7300579 | 0.85 | FOLH1 (0.70) | FOLH1PTGESALOX5PPARGCPA3 | |
| SCHEMBL5802690 | 0.85 | FOLH1 (0.56) | FOLH1PTGESALOX5PPARGCPA3 | |
| SCHEMBL8728655 | 0.83 | FOLH1 (0.54) | FOLH1PTGESALOX5PPARGCPA3 | |
| SCHEMBL2948787 | 0.83 | FOLH1 (0.54) | FOLH1PTGESALOX5PPARGCPA3 | |
| SCHEMBL27513375 | 0.83 | FOLH1 (0.68) | FOLH1PTGESALOX5PPARGCPA3 | |
| SCHEMBL28576210 | 0.83 | CSNK1E (0.54) | FOLH1CNR2MMP2MMP1MMP3 | |
| SCHEMBL2719254 | 0.82 | CA1 (0.55) | FOLH1PTGESALOX5PPARGCPA3 | |
| SCHEMBL3420503 | 0.81 | CNR2 (0.55) | CNR2MMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488131-A | Synthesis of compounds with predetermined chirality | CALIFORNIA INSTITUTE OF TECHNOLOGY | 1996-01-30 | — | — | US | disclosed |