SCHEMBL9068883

SCHEMBL9068883

CCNS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 17/20 0.55
CA1 P00915 16/20 0.55
MMP1 P03956 6/20 0.55
MMP2 P08253 6/20 0.55
MMP9 P14780 6/20 0.55
MMP8 P22894 6/20 0.55
MMP13 P45452 6/20 0.55
F2 P00734 3/20 0.40
PRSS1 P07477 3/20 0.40
PRSS2 P07478 3/20 0.40
PRSS3 P35030 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9068574 1.00 CA2 (0.55) CA2CA1MMP1MMP2MMP9
SCHEMBL9069077 1.00 CA2 (0.55) CA2CA1MMP1MMP2MMP9
SCHEMBL9069079 1.00 CA2 (0.55) CA2CA1MMP1MMP2MMP9
Sulfluramid SCHEMBL26873 1.00 CA2 (0.55) CA2CA1MMP1MMP2MMP9
Sulfluramid SCHEMBL2316089 0.98 CA2 (0.53) CA2CA1MMP1MMP2MMP9
Sulfluramid SCHEMBL28666475 0.98 CA2 (0.53) CA2CA1MMP1MMP2MMP9
SCHEMBL8105128 0.98 CA2 (0.55) CA2CA1MMP1MMP2MMP9
Sulfluramid SCHEMBL9101246 0.94 CA2 (0.55) CA2CA1MMP1MMP2MMP9
SCHEMBL19042178 0.91 CA2 (0.47) CA2CA1MMP1MMP2MMP9
Sulfluramid SCHEMBL28312518 0.91 CA2 (0.54) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5539024-A REACTION PRODUCT OF PERFLUOROALKYL SULFONAMIDE, OXYETHYLENE COMPOUND SUCH AS POLYETHERESTER, AND EPOXY COMPOUND SUCH AS NOVOLAC GLYCIDYL ETHER, PROTECTIVE COATINGS FOR PAPER, TEXTILES, LEATHER, MINERALS BAYER AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
US-5426205-A Perfluoroalkylsulphonamidoalkoxysilanes BAYER AKTIENGESELLSCHAFT (DE) 1995-06-20 US disclosed