Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070472 | 0.81 | NOS1 (0.49) | MAPTFGFR1HTTALDH1A1SLC2A1 | |
| SCHEMBL9073202 | 0.77 | SLC2A1 (0.51) | MAPTFGFR1HTTALDH1A1SLC2A1 | |
| Hydrochloric Acid SCHEMBL9073330 | 0.76 | SLC2A1 (0.53) | MAPTFGFR1HTTALDH1A1SLC2A1 | |
| SCHEMBL6850410 | 0.76 | HTT (0.47) | MAPTFGFR1HTTALDH1A1SLC2A1 | |
| SCHEMBL10753210 | 0.74 | PDE3B (0.40) | MAPTALDH1A1PDE3BPDE3AHPGD | |
| SCHEMBL9073237 | 0.74 | MAPT (0.38) | MAPTFGFR1HTTALDH1A1NOS1 | |
| SCHEMBL9073452 | 0.74 | L3MBTL1 (0.53) | MAPTHTTALDH1A1SLC2A1KDM4E | |
| SCHEMBL11829399 | 0.73 | PDE3B (0.36) | MAPTSLC2A1PDE3BPDE3AKDM4E | |
| Hydrochloric Acid SCHEMBL9070469 | 0.73 | ATM (0.53) | MAPTHTTALDH1A1SLC2A1KDM4E | |
| Hydrochloric Acid SCHEMBL9069898 | 0.73 | SLC2A1 (0.55) | MAPTHTTALDH1A1SLC2A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506235-A | Quinoline derivatives as immunostimulants | PFIZER INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0597003-A1 | QUINOLINE DERIVATIVES AS IMMUNOSTIMULANTS | PFIZER INC. (US) | 1994-05-18 | — | — | EP | disclosed |
| WO-1993003030-A1 | QUINOLINE DERIVATIVES AS IMMUNOSTIMULANTS | PFIZER INC. (US) | 1993-02-18 | — | — | WO | disclosed |