Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.31 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492601 | 0.91 | DHODH (0.37) | DHODHTAS1R3TAS1R1TAS1R2PDE2A | |
| SCHEMBL9069510 | 0.90 | DHODH (0.36) | DHODHTAS1R3TAS1R1TAS1R2PDE2A | |
| SCHEMBL8752745 | 0.87 | DHODH (0.34) | DHODHTAS1R3TAS1R1TAS1R2PDE2A | |
| SCHEMBL9116542 | 0.86 | PRKDC (0.38) | DHODHTAS1R3TAS1R1TAS1R2PDE2A | |
| SCHEMBL7574569 | 0.85 | DHODH (0.32) | DHODHPDE2A | |
| SCHEMBL977770 | 0.84 | TAS1R3 (0.37) | DHODHTAS1R3TAS1R1TAS1R2PDE2A | |
| SCHEMBL8390614 | 0.84 | PDE2A (0.33) | DHODHTAS1R3TAS1R1TAS1R2PDE2A | |
| SCHEMBL9069458 | 0.84 | DHODH (0.33) | DHODHTAS1R3TAS1R1TAS1R2PDE2A | |
| SCHEMBL8492896 | 0.84 | LMNA (0.38) | DHODHTAS1R3TAS1R1TAS1R2PDE2A | |
| SCHEMBL8489076 | 0.84 | DHODH (0.35) | DHODHPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527037-B1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-10-16 | — | — | EP | claimed |
| CN-1069267-A | HERBICIDE | RHONE POULENC AGRICULTURE (GB) | 1993-02-24 | — | — | CN | claimed |
| EP-0527037-A1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-02-10 | — | — | EP | claimed |
| CN-1042334-C | Herbicide composition containing 4-benzoyl isoxazole derivative and application thereof | RHONE POULENC AGRICULTURE (GB) | 1999-03-03 | — | — | CN | disclosed |
| CN-1141295-A | Prepn. method for 4-benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-01-29 | — | — | CN | disclosed |
| EP-0527037-B1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-10-16 | — | — | EP | disclosed |
| CN-1069267-A | HERBICIDE | RHONE POULENC AGRICULTURE (GB) | 1993-02-24 | — | — | CN | disclosed |
| EP-0527037-A1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-02-10 | — | — | EP | disclosed |