SCHEMBL7398474

SCHEMBL7398474

NCCCCCC(=O)OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](OC(=O)CCCCCN)[C@@H]1OC(=O)CCCCCN

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.44
SLC28A2 O43868 1/20 0.44
SLC29A1 Q99808 1/20 0.44
SLC28A3 Q9HAS3 1/20 0.44
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
TK2 O00142 2/20 0.43
P2RY6 Q15077 7/20 0.42
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
P2RY2 P41231 7/20 0.42
P2RY4 P51582 3/20 0.42
P2RY14 Q15391 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9069552 0.91 TK2 (0.53) SLC28A1SLC28A2SLC29A1SLC28A3MEN1
SCHEMBL9069522 0.89 CA12 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3MEN1
SCHEMBL5566835 0.87 CA12 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3MEN1
SCHEMBL26751632 0.86 LMNA (0.50) SLC28A1SLC28A2SLC29A1SLC28A3MEN1
SCHEMBL25402244 0.86 LMNA (0.50) SLC28A1SLC28A2SLC29A1SLC28A3MEN1
SCHEMBL30475853 0.84 LMNA (0.56) SLC28A1SLC28A2SLC29A1SLC28A3MEN1
SCHEMBL30475852 0.84 LMNA (0.56) SLC28A1SLC28A2SLC29A1SLC28A3MEN1
SCHEMBL18166816 0.83 TLR4 (0.46) MEN1USP2POLBKMT2ATK2
SCHEMBL5074670 0.82 LMNA (0.48) SLC28A1SLC28A2SLC29A1SLC28A3MEN1
SCHEMBL5531119 0.82 TK2 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000302675-A MEDICINE CONTAINING BASIC COMPOUND SANKYO CO LTD 2000-10-31 JP disclosed