Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 4/20 | 0.56 |
| ▸ | HTR1B | P28222 | 3/20 | 0.50 |
| ▸ | CFB | P00751 | 4/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4761139 | 0.82 | HTR1D (0.75) | HTR1DHTR1BCFBADRA2CADRA2A | |
| SCHEMBL4762027 | 0.81 | HTR1D (0.64) | HTR1DHTR1BCFBADRA2CADRA2A | |
| Hydrochloric Acid SCHEMBL11769742 | 0.80 | HTR1D (0.62) | HTR1DHTR1BCFBADRA2CADRA2A | |
| SCHEMBL9069376 | 0.76 | CFB (0.51) | HTR1DCFBADRA2CADRA2AADRA2B | |
| SCHEMBL6054568 | 0.74 | ADRA2A (0.67) | HTR1DHTR1BADRA2CADRA2AADRA2B | |
| SCHEMBL4760243 | 0.72 | HTR1D (1.00) | HTR1DHTR1BCFBADRA2CADRA2A | |
| Hydrochloric Acid SCHEMBL29384552 | 0.71 | HTR1D (0.97) | HTR1DHTR1BCFBADRA2CADRA2A | |
| SCHEMBL11187565 | 0.69 | HTR1D (0.76) | HTR1DHTR1BCFBADRA2CADRA2A | |
| SCHEMBL11185198 | 0.69 | HTR1D (0.58) | HTR1DHTR1BCFBADRA2CADRA2A | |
| SCHEMBL5612003 | 0.69 | ADRA2A (0.43) | HTR1DHTR1BCFBADRA2CADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527830-A | Drugs for the treatment of cardiac arrest and other shock states | THE OHIO STATE UNIVERSITY (US) | 1996-06-18 | — | — | US | disclosed |