Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9070321

C=C(CCN(C)C)C(=O)O.N

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.35
EGFR P00533 2/20 0.34
KDM4A O75164 12/20 0.33
KDM4C Q9H3R0 12/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
KDM5A P29375 1/20 0.33
KDM7A Q6ZMT4 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28345645 0.98 KDM4A (0.36) TET2EGFRKDM4AKDM4CKDM5A
SCHEMBL22345 0.98 TET2 (0.37) TET2EGFRKDM4AKDM4CTET3
SCHEMBL30785151 0.98 TET2 (0.37) TET2EGFRKDM4AKDM4CTET3
Hydrochloric Acid SCHEMBL1155810 0.95 KDM4A (0.37) TET2EGFRKDM4AKDM4CTET3
Acetic Acid SCHEMBL11512957 0.93 TET2 (0.34) TET2EGFRKDM4AKDM4CTET3
Bromomethane SCHEMBL7095815 0.93 TET2 (0.34) TET2EGFRKDM4AKDM4CTET3
Chloromethane SCHEMBL124968 0.93 TET2 (0.39) TET2EGFRKDM4AKDM4CTET3
SCHEMBL4242756 0.89 KDM4A (0.38) KDM4AKDM4CKDM5AKDM7APHF8
SCHEMBL8736374 0.89 MAPT (0.39) TET2EGFRKDM4AKDM4CTET3
Sulfuric Acid SCHEMBL1155538 0.89 GSR (0.36) TET2EGFRKDM4AKDM4CTET3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525450-A QUATERNARY AMMONIUM AND ACID GROUP CONTAINING POLYMER SEGMENTS IN NONPOLAR LIQUID XEROX CORPORATION (US) 1996-06-11 US disclosed